This letter, written by Dr. Jamie McManus, Chair of Medical Affairs at Shaklee, is addressed to physicians to introduce new Shaklee Blood Pressure and to provide them with additional information about the product. Its purpose is for people to take to their doctor to help assess whether the Blood Pressure product is advisable based on their current health and medication status. We strongly urge all product users to discuss the usage of this product with their physicians, especially if blood pressure monitoring is occurring.
Please allow me to introduce a new dietary supplement from Shaklee Corporation that is designed to provide a more
natural approach to help support arterial health and function as well as contribute to maintaining already healthy
blood pressure levels. The product is intended to be used in conjunction with proven diet and lifestyle adjustments,
in particular the DASH diet and weight loss as needed. We strongly urge all product users to discuss the usage of this
product with their physicians, especially if blood pressure monitoring is occurring.
The DASH diet has long been accepted and recommended by physicians to help patients reduce blood pressure either
with an antihypertensive medication or as a stand-alone intervention when blood pressure is only modestly elevated.i
It was long thought that antioxidants were responsible for the DASH diet’s proven ability to provide up to a 10 mm Hg
drop in both systolic and diastolic pressures, but the latest research is showing that dietary inorganic nitrates may be
the reason for its efficacy.ii Foods high in dietary inorganic nitrite and nitrate include: celery, beetroot, spinach, and
others. In a meta-analysis of 16 clinical crossover studies, sodium nitrate and beetroot juice were able to significantly
reduce systolic blood pressure.iii
Our Shaklee Blood Pressure, a two-tablet per day product, delivers 500 mg of inorganic nitrates from a proprietary 1,300
mg vegetable blend comprised of beetroot juice, spinach, and potassium nitrate. The product is designed to support
already healthy blood pressure levels. The label and supplement facts are included below.
Dietary inorganic nitrates are generally believed to be quite safe. While there are no known drug interactions using
supplemental dietary inorganic nitrates, caution is advisable in certain populations. Antihypertensive and cardiac drugs
(including other organic nitrates) and supplemental nitrates may have potential additive effects; while side effects have
not been described, they are theoretically possible. Monitoring of INR in patients taking Coumadin is also warranted. We
believe adding in our supplemental inorganic nitrate formula can safely contribute to maintaining healthy blood pressure
already in the normal range.
Shaklee has a long history in the nutritional supplement industry, beginning when our founder, Dr. Forrest C. Shaklee,
first developed a multivitamin in 1915. Shaklee Corporation was founded in 1956 and is committed to creating products
that are relevant to supporting people’s health and well-being.
Thank you for your time and please feel free to contact me with any questions you may have.
Jamie McManus, M.D., FAAFP
Chair, Medical Affairs & Health Sciences
Appel LJ, Brands, MW, Daniels SR et al, Dietary approaches to prevent and treat hypertension: a scientific statement from the
American Heart Association. Hypertension, 2006 Feb, 47 (2): 296-308.
iiHord NG, Tang Y, Bryan NS. Food sources of nitrates and nitrites: the physiologic context for potential health benefits. Am J Clin
Nutr. 2009 Jul; 90 (1): 1-10. PubMed PMID: 19439460.
iiiSiervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults:
a systematic review and meta-analysis. J Nutr. 2013 Jun; 143 (6): 818-26. PMID: 23596162.”